Basic Science Seminar
Inter-organ communication in liver disease
Wed. 21 June, 8:30 – 18:45 CET
The seminar aims to foster interaction between leaders-in-the-field and the audience. It contains multiple short duo-lectures, with first a more general ten-minute overview of the topic, followed by a more in-depth ten-minute presentation by a talented fellow, and finally an extensive Q&A with the audience. Access to the Basic Science Seminar is included in your congress registration fee.
Inter-organ communication is a crucial aspect of physiology and essential for the maintenance of health. The one-day Basic Seminar at EASL Congress 2023 will focus on the bidirectional communication between the liver and other organs. It will detail how the liver impacts the physiology of multiple organs and, reciprocally, how other organs regulate hepatic physiology. The seminar will also explore how various liver diseases stem from an imbalance in the communication between the liver and other organs.
The seminar seeks to promote interaction between field leaders and the audience through four sessions of short duo lectures. Each session starts with a 10-minute general overview, followed by a 10-minute in-depth presentation by a talented colleague, and ends with a 10-minute Q&A. The programme covers the field of cross-talk between the liver and other organs. The seminar appeals to both basic science professionals and clinicians seeking to deepen their understanding of inter-organ physiological networks.
By gaining a deeper understanding of these concepts, you can inform your own research and stay updated on the field’s future directions, including new therapeutic approaches. We hope this symposium will be informative and useful for your hepatology practice or research.
Basic Science Seminar organisers
- Understand the significance of the gut-liver axis and the microbiome in liver disease.
- Recognise the crucial role of endocrine factors and non-coding RNAs in controlling liver functions.
- Understand the role of the liver in orchestrating systemic metabolism and immune homeostasis.
- Appreciate the importance of intercellular communication between various cell types within the liver.
Summary per session:
The first session explains the communication between the liver and the microbiome through the exchange of signals and substances that influence each other’s functions and health.
Signals affecting liver function
This session will give an overview on liver metabolism with particular reference to the control of lipid metabolism by the CNS and on the role of mitochondria in the gut-liver axis.
In this session, liver cellular and immune responses in the context of peripheral activities including stress, exercise, bile acids metabolism and the circadian clock are summerised.
Communication within the liver
This session will give an overview on the communication between resident cells in the liver and new methodologies to study liver diseases.